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Cytology (also known as cytopathology) involves examining cells from bodily tissues or fluids to determine a diagnosis. A certain kind of physician, called a pathologist, will look at the cells in the tissue sample under a microscope and look for characteristics or abnormalities in the cells.

There are two main kinds, or branches, of cytology: exfoliative cytology and intervention cytology.

Healthcare providers can use cytology tests for almost all areas of your body. Some common types of cytology tests include:

  • Gynecologic cytology.
  • Urinary cytology.
  • Breast cytology.
  • Thyroid cytology.
  • Lymph node cytology.
  • Respiratory cytology.
  • Eye cytology.
  • Ear cytology.

Intervention cytology is a branch of cytology in which your healthcare provider has to “intervene” with your body to get a sample of cells to test, meaning they have to pierce your skin in some way to get a sample of cells.

The most common type of intervention cytology is fine-needle aspiration (FNA). A healthcare provider will inject a thin needle into the area that they need to sample and draw out fluid. A pathologist then examines the cells in the fluid under a microscope.