Histopathology

A specialist doctor (histologist) performs a histopathology test and examines the tissue sample under a microscope. They usually process and cut the tissue into thin layers known as sections, which are then stained and observed. The histologist then documents the details of the tissue they are observing to create a histology report.

Here is a brief overview of how histopathology test is performed:

• Tissue sample collection: During a biopsy or surgical procedure, a small piece of lung tissue is removed for analysis. This sample is then sent to a pathology laboratory for further examination.
• Tissue processing: The tissue sample is processed by removing any excess blood, fat or connective tissue. It is then treated with chemicals to preserve its cellular structure. Embedding and sectioning: The processed tissue sample is embedded in paraffin wax and sliced into thin sections using a microtome. These sections are placed on glass slides for microscopic examination.
• Staining: The tissue sections are stained using various dyes to enhance the visibility of different cellular components. This allows pathologists to identify any abnormalities. Microscopic examination: A pathologist examines the stained tissue sections under a microscope. They look for any changes in cell size, shape, organisation or the presence of cancerous cells.
• Interpretation and reporting: Once the examination is complete, the pathologist prepares a detailed report describing their findings. This report helps guide further treatment decisions.

The histological reports created for different cell types can be complex, which include

• The description of the appearance of the tissue sample
• A synoptic report that gives detailed findings of the relevant case
• A diagnosis
• The histopathologist's comments

As this is a reasonably complex report, it is best to go over it with your healthcare provider to get the correct diagnosis and path for treatment if needed. However, knowing what is a histopathology test and the components of the results can help you be a little better prepared for the conversation with your healthcare provider.

Histopathology involves the diagnosis and study of diseases of the tissues by examining tissues and/or cells under a microscope.