Immunoassay

Immunoassay Tests are biochemical tests that detect disease and works on the principle of antigen-antibody reaction. It aims at measuring the presence and the concentration of an analyte. Researchers and health care professionals utilize immunoassays testing to detect different kinds of antibodies.

Surmodics™ IVD provides immunoassay developers the critical components they need to build reliable, robust, and accurate immunoassay tests. Our broad portfolio includes the industry’s gold standard in protein stabilizers/blocking buffers designed to increase sensitivity and specificity while decreasing non-specific binding. We also offer best-in-class detection substrates for color (TMB, ABTS, PNPS, BCIB/NBT) and light (Chemiluminescent) development as well as a selection of accessory reagents including our high-performance diluents designed to reduce matrix interferences including Human Anti-Mouse Antibodies (HAMA) and Rheumatoid Factor (RF) interferences.

We also manufacture and supply a line of microarray slides and surface technology as well as supply high quality antigens and antibodies from our partner company, DIARECT™ located in Germany.

Immunoassay testing works by using antibodies to detect small biological substances in the blood and other bodily fluids. The method follows the aspect that particular antigens binds to specific newly introduced antibodies, thereby stimulating an immune response. This refers to specificity, as antibodies are highly specific to analytes such as hormones, nucleoproteins, and peptides, among others. Provided the immunoassay test used reagents are pure, detection of analytes becomes successful through the formation of antigen-antibody complexes. A color change occurs, which indicates the presence of the analyte in question. The observed color symbolizes the amount of targeted molecule present in the test solution.